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An article published on The American Journal on Addictions stated that pregnant women who were dependent on opioids were strongly considering antagonist treatment, especially one which involves the using naltrexone to combat their substance abuse disorder. Using two separate drugs to lose weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it you need to err on the side of caution and let the FDA do its job and demand some study be done in order that the public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on the medications. Researchers discovered that participants using this drug for the year, lost excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which might be made up of more than one active ingredient, which might make them far better and safer. Combo-pilling is the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular is the fact that as of right now there aren't long term prescription slimming capsules that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure level and heartrate, and shouldn't be used in individuals with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure levels and heartrate and must 't be used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. New UCLA study on smokers with mental, drug, and alcohol problems